Cisplatin h460
WebDec 16, 2015 · H460 lung cancer cells increased cisplatin sensitivity and showed reduced repair of both . intrastrand and interstrand adducts suggesting that the mechanism of sensitivity is primarily . WebCisplatin induces A549 and H460 cell apoptosis via the mitochondrial‑associated pathway (A and B) After treatment with 10, 20 and 40 µM cisplatin, cell apoptosis was detected using flow...
Cisplatin h460
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WebSep 1, 2006 · Figure 2C shows that H460-pMEP 4-MKP-1 cells treated with CdSO 4 were more resistant to both doses of cisplatin compared with the control H460-pMEP 4 vector cells . Thus, these results indicate that overexpression of MKP-1 plays a critical role in cisplatin resistance in the H460 human lung cancer cell. WebJul 28, 2024 · Cisplatin induces an autophagic response in lung cancer H460 cells. To investigate the autophagic response, the alteration of autophagy marker proteins was …
WebJul 13, 2024 · a H460 cells were reprogrammed using the Stemgent mRNA Reprogramming System (Reprocell, Beltsville, MD, USA). Schedule for establishing R-H460 cells by transfecting the mRNAs of reprogramming... WebJun 20, 2024 · H460-Cis and A549-Cis cells were treated with 2 μ g/mL cisplatin to maintain cisplatin resistance character. All human cell lines have been authenticated using short tandem repeat (STR) profiling. Cells were maintained at 37°C in a humidified atmosphere with 5% CO 2.
WebJan 26, 2024 · Emodin enhances cisplatin-induced DNA damage in A549 and H460 cells Cisplatin mainly kills tumor cells by inducing DNA damage ( 30 ). The effect of emodin on the chemosensitivity of A549 and H460 … WebMay 27, 2024 · Epithelial non-small lung cancer H460 cells (generated from a pleural effusion of a patient with large cell lung cancer) and H1299 cells (derived from an NSCLC carcinoma) were maintained in RPMI supplemented with 10% fetal bovine serum (FBS) (Life Technologies, Grand Island, NY, USA).
WebApr 13, 2024 · Cisplatin‑resistant A549 (A549/CDDP) and H460 (H460/CDDP) cells were first established and were then transfected with negative control small interfering (si)RNA (si‑NC) or TRPC1 siRNA (si‑TRPC1). Cells were then treated with 740 Y‑P, a PI3K/Akt agonist. Subsequently, the sensitivity of A549/CDDP and H460/CDDP cells to CDDP …
WebConversely, H460 cisplatin-resistant cells showed increased tendency to develop bone metastasis. Gene expression analysis showed that several genes involved in tumor … floating cabins on the tennessee riverWebThe IC 50 concentrations detected in A549 and H460 cisplatin-resistant cell lines and the parental cell lines. Source publication ABCG2 regulates the pattern of self-renewing … great homes bienes raicesWeb2 days ago · LUAD cell lines H1299, H460, A549, H1975, CALU1 and CALU6, lung fibroblasts HEL299, lung bronchial epithelial cell line HBEC, normal human bronchial epithelium cell line BEAS2B, kidney embryonic ... great homes caWebMay 28, 2024 · Cells endogenously expressing high (A549 and H460 cells) versus low (EBC-1, CRL-5889 and HTB-182 cells) CDCA3 levels were untreated, cisplatin treated for 12 h (cisplatin) or cultured in... floating cabins on lake murray in oklahomaWebInjection, cisplatin, powder or solution, 10 mg: BETOS Code: O1D - Chemotherapy: Action Code: N - No maintenance for this code: Type of Service Code: 1 - Medical care: Pricing … gre at home schedule testWebMay 1, 2024 · Cisplatin-resistant versions of the A549, H1299, and H460 cell lines were generated by continuous drug exposure. The long-term metabolic changes, as well as, the early response to cisplatin treatment were analyzed in both, parental and cisplatin-resistant cell lines. great homes australiaWebC is-diamminedichloroplatinum(II) (cisplatin) is the most celebrated metal-based chemotherapeutic in the history of modern medicine.The discovery of its anticancer effects was not only opportune [1,2,3], especially during a period when cancer prevention was desperately needed, but also because medical oncology did not yet exist as a clinical … great homeschool conference